ISSN 1662-4009 (online)

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Yearbook of Paediatric Endocrinology 2020

8. Adrenals

Food for Thought

ey0017.8-17 | Food for Thought | ESPEYB17

8.17. Plasma renin measurements are unrelated to mineralocorticoid replacement dose in patients with primary adrenal insufficiency

R Pofi , A Prete , V Thornton-Jones , J Bryce , SR Ali , Ahmed S Faisal , A Balsamo , F Baronio , A Cannuccia , A Guven , T Guran , F Darendeliler , C Higham , W Bonfig , L de Vries , TASS Bachega , MC Miranda , BB Mendonca , V Iotova , M Korbonits , NP Krone , R Krone , A Lenzi , W Arlt , RJ Ross , AM Isidori , JW Tomlinson

To read the full abstract: J Clin Endocrinol Metab. 2020; 105(1): dgz055. PMID: 31613957.Mineralocorticoid (MC) replacement therapy along with glucocorticoid (GC) replacement is crucial to avoid life-threating adrenal crises in Addison´s disease (AD) and in classical CAH (1–3). MC is administered with the aim of achieving plasma renin concentration (PRC) within the upper limit of ...

ey0017.8-18 | Food for Thought | ESPEYB17

8.18. Interaction between hypothalamic-pituitary-adrenal axis genetic variation and maternal behavior in the prediction of amygdala connectivity in children

E Pozzi , CA Bousman , JG Simmons , N Vijayakumar , O Schwartz , M Seal , MBH Yap , NB Allen , SL Whittle

To read the full abstract: Neuroimage. 2019; 197:493–501. PMID: 31077842.A large body of evidence suggests that the early environment can influence the health and wellbeing in children later in life. Variability in susceptibility to environmental stimuli might be mediated by interactions between genetic variations and the environment. The hypothalamic-pituitary adrenal (HPA) axis is th...